Trump Launches AI Initiative 'Genesis Mission' to Boost Research

Published
November 25, 2025
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Technology
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President Trump signed an executive order on Monday launching the 'Genesis Mission,' a new initiative aimed at accelerating scientific discovery through the use of artificial intelligence. According to CBS News, the order directs the Energy Department and its national labs to create an integrated AI platform utilizing their existing and future supercomputers. The initiative is positioned as a significant federal effort, with Michael Kratsios, the president's science adviser, stating it represents the largest mobilization of federal scientific resources since the Apollo program. The Genesis Mission aims to enhance research in various fields, including health care, engineering, and energy, by analyzing large data sets to expedite breakthroughs, particularly in disease therapies. Kratsios emphasized that the initiative will enable scientists to conduct experiments and simulations at unprecedented speeds, potentially reducing discovery timelines from years to mere days or hours.

NBC News reported that the Genesis Mission is described as comparable in urgency and ambition to the Manhattan Project. The executive order outlines steps to expand computational resources, enhance access to extensive federal datasets, and foster real-world applications in critical scientific fields. The order also mandates the establishment of a new American Science and Security Platform, which will centralize the required infrastructure for this ambitious initiative. This platform is expected to provide researchers with the necessary computing power and datasets to train AI models effectively.

The Genesis Mission will also facilitate increased public-private partnerships in AI development. Within 90 days, Secretary of Energy Chris Wright is tasked with identifying systems and datasets available to support the program, including resources from industry partners. This initiative seeks to address barriers to data-sharing, enabling researchers to utilize the federal government's vast but often decentralized datasets to train AI systems. With additional computing resources and enhanced access to data, the initiative aims to tackle practical scientific challenges within 270 days, focusing on areas such as advanced manufacturing, biotechnology, and nuclear fission and fusion.

Experts are optimistic about the potential of the Genesis Mission. Keegan McBride from the Tony Blair Institute highlighted that AI could fundamentally transform the scientific and research landscape. The announcement builds upon the National Artificial Intelligence Research Resource, or NAIRR, which was established in 2020 to create a robust national research infrastructure for AI and innovation. Lynne Parker, who co-chaired the NAIRR task force, stated that sustained federal support for AI research is crucial for progress in the field, arguing that long-term investment is essential to maintain U.S. leadership in technologies that will shape the economy and national security.

The Genesis Mission is expected to leverage existing supercomputers at the Department of Energy's 17 national labs while plans are in motion to develop additional supercomputing capabilities. The initiative comes at a time when the U.S. Department of Energy is partnering with companies like AMD to enhance supercomputing resources, further underscoring the importance of collaboration between public and private sectors in advancing AI research and applications. White House officials expressed confidence that the advancements achieved through this initiative could lead to significant breakthroughs in health sciences and beyond, marking a pivotal moment for AI research in the United States.

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