NFL Week 10 Preview: Key Matchups and Predictions

Published
November 09, 2025
Category
Sports
Word Count
353 words
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As NFL Week 10 approaches, attention is sharply focused on several critical matchups that could significantly affect playoff standings. The Buffalo Bills will visit the Miami Dolphins for a key AFC East clash, with the Bills entering as 9.5-point favorites, according to Syracuse.com. Buffalo boasts a 78% chance of victory, bolstered by a solid performance from quarterback Josh Allen and an offense looking to capitalize on last week's momentum. Meanwhile, the Dolphins' offense, led by Tua Tagovailoa, will aim to counter with their explosive playmakers, including DeVon Achane and Jaylen Waddle. The game promises to be a thrilling showcase of offensive talent, with a projected total of just under 50 points. Dimers.com predicts a final score of 28-20 in favor of the Bills, further emphasizing the stakes of this matchup in the context of the AFC playoff race.

On the other hand, the Cleveland Browns will host the New York Jets, who are struggling at 1-7 this season. Cleveland.com reports that the Browns view this matchup as a 'no excuse game,' given the Jets' poor defensive rankings, allowing nearly 28 points per game and struggling against the run. The Jets are also facing uncertainty at quarterback, with neither Justin Fields nor Tyrod Taylor establishing firm control over the position. This game, set to kick off at 1 PM EST in East Rutherford, New Jersey, is critical for the Browns as they seek to solidify their playoff ambitions.

Weather conditions may play a role in the Jets-Browns clash, with temperatures expected around 60 degrees and a rising chance of rain as the game progresses, according to Gang Green Nation. This could influence game strategies, particularly for the Browns, who are looking to establish a strong running game against a vulnerable Jets defense.

In summary, Week 10 of the NFL season features pivotal matchups with high stakes. The Bills aim to assert their dominance in the AFC East against the Dolphins, while the Browns look to capitalize on their home-field advantage against a struggling Jets team. Both games promise to be essential for playoff positioning as teams push toward the final stretch of the season.

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