San Francisco 49ers Summary

The San Francisco 49ers made significant roster moves ahead of their Week 15 matchup against the Tennessee Titans. Notably, they placed wide receiver Brandon Aiyuk on the reserve/left squad list, effectively ending his season and likely his tenure with the team, as reported by multiple sources including NBC Sports Bay Area.

Additionally, running back Christian McCaffrey was added to the injury report due to a back injury but is expected to play, following a week where he was also listed with an illness but practiced fully on Friday.

The 49ers have elevated a pair of defenders in preparation for the game, indicating a busy week for the organization as they gear up for their upcoming challenge against the Titans, who will also have former 49ers players on their roster returning to Levi's Stadium.