Indianapolis Colts Summary

The Indianapolis Colts are gearing up for a significant matchup against the San Francisco 49ers on Monday Night Football in Week 16. Notably, the Colts will be without their top two cornerbacks, as Sauce Gardner has been ruled out for the game, which could impact their defensive strategy against the 49ers' offense.

On the positive side, the Colts will welcome back defensive tackle DeForest Buckner, who is expected to contribute against his former team, as confirmed by head coach Shane Steichen. In contrast, the 49ers will be missing wide receiver Ricky Pearsall and linebacker Renardo Green, adding to the intrigue of this matchup.

As the Colts prepare, they aim to capitalize on a potentially vulnerable 49ers run defense, with running back Jonathan Taylor poised to have a significant impact in the game. The Colts' injury report indicates that left tackle Bernhard Raimann is listed as questionable, which may further complicate their offensive line situation against a formidable opponent.