Upcoming Clash: Arizona Cardinals vs. Seattle Seahawks Preview

As the Arizona Cardinals face off against the Seattle Seahawks, this pivotal Week 10 matchup holds significant implications for both teams' playoff prospects. With a record of three wins and five losses, the Cardinals are eager to keep their hopes alive against a formidable rival that currently stands at six wins and two losses. The game is set to take place on November 9, 2025, at State Farm Stadium in Glendale, Arizona. It will be broadcast nationally on CBS, with local radio coverage on Arizona Sports 98.7 FM. The betting line currently favors the Seahawks by six and a half points, underscoring the challenges ahead for the Cardinals as they look to upset their division rivals.

Both teams enter the game with notable injury concerns. The Cardinals are particularly vulnerable in their secondary, having faced multiple injuries throughout the season. As noted by Revenge of the Birds, the Seahawks' potent passing game, which ranks among the best in the NFL, may exploit this weakness. The Seahawks' strategy will likely involve aggressive passing, especially considering the Cardinals' struggles to maintain defensive integrity against powerful offenses.

On the Seahawks' side, they too are grappling with injuries that have affected their roster. Key players have been sidelined, including defensive tackle Jarran Reed, who was unexpectedly ruled out just days before the game due to wrist and thumb injuries. Reed, who has been a significant contributor with one and a half sacks and six quarterback hits this season, will be missed on the defensive line. His absence places additional pressure on younger players like Byron Murphy II, a first-round draft pick in 2024, and veteran Mike Morris, who has been elevated to a captain role for this game, indicating the team's reliance on him to step up.

The Seahawks have also turned to their practice squad to fill gaps left by injuries, particularly in the receiving corps, where only two of five wide receivers were active in their previous game. This situation may lead to an increased role for newly acquired Rashid Shaheed, who joined the team via a trade with the New Orleans Saints. With uncertainty surrounding the health of current receiving options, the Seahawks will need to adapt their game plan accordingly.

This matchup not only serves as a test of resilience for the Cardinals but also highlights the strategic adjustments both teams must make in light of their injuries. The outcome could significantly impact the NFC West standings, with the Seahawks aiming to maintain their lead and the Cardinals fighting for relevance in the playoff race. As both teams prepare for this crucial game, the stakes are high, making for an exciting showdown that promises to deliver both drama and intensity on the field.