Arizona Cardinals Summary

Published
November 13, 2025
Category
NFL
Word Count
248 words
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The Arizona Cardinals are facing significant challenges as they prepare for their upcoming game against the San Francisco 49ers. Notably, wide receiver Marvin Harrison Jr. will be sidelined after undergoing surgery for appendicitis, as reported by multiple sources including CBS Sports.

This absence is a significant blow to the Cardinals' offense, which is already dealing with injuries. Furthermore, the team has officially placed wide receivers Simi Fehoko and Zay Jones on injured reserve due to their respective injuries, which only compounds the issues facing the offense ahead of the Week 11 matchup against the 49ers, as noted by ESPN.

The Cardinals are now in a position where they will need to adjust their game plan significantly without some of their top receiving threats, potentially leading to a more challenging game against a 49ers defense that is looking to bounce back after recent struggles.

Meanwhile, the 49ers are preparing for their own quarterback situation as Brock Purdy's return to starting duties is in question, with the team pushing him aggressively in practice this week, according to reports from 49ers beat writers.

The combination of the Cardinals' offensive injuries and the uncertain status of Purdy creates an intriguing dynamic for the upcoming game, as both teams will be looking for ways to exploit the other's weaknesses.

As the Cardinals gear up for this crucial division matchup, the impact of these injuries will be closely monitored as they strive to maintain competitiveness in what has been a challenging season thus far.

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